Circadian Clocks: 50 Years On
نویسندگان
چکیده
منابع مشابه
Circadian Biology: Clocks within Clocks
A small cluster of approximately 20,000 neurons in the ventral hypothalamus provide the body with key time-keeping signals and drive circadian rhythms. This circadian clock exhibits surprisingly complex substructures, with inputs from the retina, and outputs to other brain structures. Rather little is known of the neurotransmitters involved, or their regulation.
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Clock (CLK), is replaced by an analogous protein, D-80336 Munich NPAS2 (also called MOP4). Like CLK, it heterodimerizes Germany with BMAL1 (also called MOP3) to drive transcription of a collection of downstream effectors, including mper1, mper2, and mcry1. Further experiments demonstrate Andre Gide wrote: " If I were not there to make them that, like in the feedback loop where CLK and BMAL1 acq...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Symposia on Quantitative Biology
سال: 2007
ISSN: 0091-7451
DOI: 10.1101/sqb.2007.72.057